thumb|300px|right|Issen training in Onimusha 3 Issen is the famous 'one hit kill,' 'counterattack,' 'timed-attack,' that kills most enemies in one strike.
It happens when the enemy attacks you or is in a position that's
vulnerable to Issen. When pressed at the right time, your player
character will dodge the enemies' attacks like it was nothing and
strikes the enemy with his equipped weapon, killing it instantly.